T and B lymphocytes in canine lymphosarcoma.

Canine Lymphosarcoma : Diagnosis and Treatment

This article discusses the diagnostic and treatment approach to canine lymphosarcoma (LSA). Several conclusions can be drawn from the extensive body of studies on canine LSA in clinical and pathologic medicine: It is now recognized that this disease has great clinical and histologic heterogeneity; in most cases, survival can be improved with combination chemotherapy; and drug resistance is a ma...

Wnt signaling in B and T lymphocytes.

Wnt signaling has been shown to be critical for proper embryonic development as well as growth regulation of certain adult tissues. Defects in Wnt pathways have additionally been associated with a number of human cancers. However, it is only recently that a role for Wnts in the immune system has come to be appreciated. Wnts have now been shown to play significant roles in early stage developmen...

Surface Globulins of T and B Lymphocytes

The concept that lymphocytes recognize antigens by means of a surface receptor molecule of immunoglobulin (Ig) character has come to be widely accepted (1-3). Direct study of such receptors in the mouse by means of antiglobulin reagents labeled with either fuorescent (4, 5) or radioisotope (3, 6-8) markers has revealed a dense coating of surface immunoglobulins on nonthymus-derived or B lymphoc...

Mice Lacking Mature T and B Lymphocytes

Regulation of human gut B lymphocytes by T lymphocytes.

The aims of this study were first, to assess whether or not immunoglobulin secretion from human gut mucosal B lymphocytes can be modified by T lymphocytes, and second whether human gut mucosal T lymphocytes are capable of regulating mucosal B lymphocyte function. T and B lymphocyte enriched cell populations were isolated from gut mucosa and co-cultured in varying proportions. Addition of T lymp...